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E74 like ETS transcription factor 4 (Elf4) Peptide

Elf4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976283
$160.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 16 Business Days

Quick Overview for E74 like ETS transcription factor 4 (Elf4) Peptide (ABIN976283)

Target

Elf4 (E74 like ETS transcription factor 4 (Elf4))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-ELF4 antibody (Catalog #: ARP32248_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Elf4 (E74 like ETS transcription factor 4 (Elf4))

    Background

    ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.

    Alias Symbols: ELFR, MEF

    Protein Interaction Partner: FBXO4,FBXO7,PML,RUNX1,SKP2,UBB,RUNX1

    Protein Size: 663

    Molecular Weight

    71 kDa

    Gene ID

    2000

    NCBI Accession

    NM_001421, NP_001412

    UniProt

    Q99607
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