Endoglin (ENG) Peptide
ENG
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all Endoglin (ENG) products
- Endoglin (ENG)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ENG antibody (Catalog #: ARP33068_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Endoglin (ENG)
- Background
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Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
Alias Symbols: END, ORW, HHT1, ORW1, CD105
Protein Interaction Partner: ENG,ACVR1,ACVR2A,BMP2,BMP7,ENG,INHBA,TCTEX1D4,TGFB1,TGFB2,TGFB3,TGFBR1,TGFBR2,TGFBR3,ACVR1,ACVR2A,ACVR2B,BMP2,BMP7,TGFBR1,TGFBR2
Protein Size: 625 - Molecular Weight
- 68 kDa
- Gene ID
- 2022
- NCBI Accession
- NM_000118, NP_000109
- UniProt
- P17813
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