Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2) (N-Term) Peptide
ENPP2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976357
Quick Overview for Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2) (N-Term) Peptide (ABIN976357)
Target
ENPP2
(Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- YTLATGLYPE SHGIVGNSMY DPVFDATFHL RGREKFNHRW WGGQPLWITA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ENPP2 Antibody(ARP44907_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
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Background
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The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ATX, ATX-X, FLJ26803, LysoPLD, NPP2, PD-IALPHA, PDNP2, AUTOTAXIN
Protein Size: 863 -
Molecular Weight
- 95 kDa
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Gene ID
- 5168
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NCBI Accession
- NM_001040092, NP_001035181
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UniProt
- Q13822
Target
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