Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) (Middle Region) Peptide
ENPP6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976358
Quick Overview for Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) (Middle Region) Peptide (ABIN976358)
Target
ENPP6
(Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ENPP6 antibody (Catalog #: ARP53158_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))
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Background
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ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. ENPP6 hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.
Alias Symbols: MGC33971, NPP6
Protein Size: 440 -
Molecular Weight
- 50 kDa
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Gene ID
- 133121
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NCBI Accession
- NM_153343, NP_699174
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UniProt
- Q6UWR7
Target
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