erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (Middle Region) Peptide
EPB49
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976377
Quick Overview for erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (Middle Region) Peptide (ABIN976377)
Target
Dematin (EPB49)
(erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- KKPPIYKQRE SVGGSPQTKH LIEDLIIESS KFPAAQPPDP NQPAKIETDY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EPB49 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
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Background
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Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation.
Alias Symbols: DMT, FLJ78462, FLJ98848, EPB49
Protein Interaction Partner: DISC1,ACTB,ACTC1,DYNC1LI2,EPB42,PRKACA,PROCR,PTOV1,SNRPD2,SPTB,DYNC1LI2,PROCR,PTOV1,SNCA
Protein Size: 405 -
Molecular Weight
- 45 kDa
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Gene ID
- 2039
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NCBI Accession
- NM_001978, NP_001969
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UniProt
- Q08495
Target
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