Erythropoietin Receptor (EPOR) (N-Term) Peptide
EPOR
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN976392
Quick Overview for Erythropoietin Receptor (EPOR) (N-Term) Peptide (ABIN976392)
Target
EPOR
(Erythropoietin Receptor (EPOR))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- SVRFWCSLPT ADTSSFVPLE LQVTEASGSP RYHRIIHINE VVLLDAPAGL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Epor Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EPOR (Erythropoietin Receptor (EPOR))
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Background
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Epor is a receptor for erythropoietin. Epor mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, Epor can also activate STAT1 and STAT3. Epor may also activate the LYN tyrosine kinase.
Alias Symbols: -
Protein Interaction Partner: Crkl,Jak2,Kit,Lyn,Lyn,Pik3r1,Ptpn1,Stat5a,Stat5b
Protein Size: 507 -
Molecular Weight
- 55 kDa
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Gene ID
- 13857
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NCBI Accession
- NM_010149, NP_034279
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UniProt
- P14753
Target
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