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Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) Peptide

ETFA Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN976459
  • Target See all ETFA products
    ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))
    Origin
    Human
    Source
    • 7
    • 3
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ETFA antibody (Catalog #: ARP54289_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))
    Background
    ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: EMA, GA2, MADD

    Protein Interaction Partner: ETFB

    Protein Size: 333
    Molecular Weight
    35 kDa
    Gene ID
    2108
    NCBI Accession
    NM_000126, NP_000117
    UniProt
    P13804
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