Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) Peptide
Quick Overview for Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) Peptide (ABIN976459)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ETFA antibody (Catalog #: ARP54289_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) peptide
ETFA Reactivity: Human Host: Escherichia coli (E. coli) WB, ELISA, IP, SDS Dithiothreitol (DTT)
Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) peptideETFA Reactivity: Mouse Host: Escherichia coli (E. coli) WB, ELISA, IP, SDS Dithiothreitol (DTT)
Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) peptideETFA Reactivity: Rat Host: Escherichia coli (E. coli) WB, ELISA, IP, SDS Dithiothreitol (DTT)
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))
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Background
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ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EMA, GA2, MADD
Protein Interaction Partner: ETFB
Protein Size: 333 -
Molecular Weight
- 35 kDa
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Gene ID
- 2108
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NCBI Accession
- NM_000126, NP_000117
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UniProt
- P13804
Target
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