MDS1 and EVI1 Complex Locus (MECOM) (Middle Region) Peptide
MECOM
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976489
$160.46
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100 μg
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Quick Overview for MDS1 and EVI1 Complex Locus (MECOM) (Middle Region) Peptide (ABIN976489)
Target
MECOM
(MDS1 and EVI1 Complex Locus (MECOM))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- KHPSVGDNKP VELQPERSSE ERPFEKISDQ SESSDLDDVS TPSGSDLETT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EVI1 Antibody(ARP58566_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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Background
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EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity.
Alias Symbols: AML1-EVI-1, EVI-1, MDS1-EVI1, MGC163392, PRDM3, EVI1, MDS1
Protein Interaction Partner: CREBBP,CTBP1,CTBP2,HDAC1,HDAC4,KAT2B,SMAD3,HDAC1,MECOM,CREBBP,CTBP1,EHMT2,HDAC1,HDAC4,KAT2B,MBD3,SMAD1,SMAD2,SMAD3,SMAD4,SUV39H1
Protein Size: 1051 -
Molecular Weight
- 118 kDa
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Gene ID
- 2122
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NCBI Accession
- NM_005241, NP_005232
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UniProt
- Q03112
Target
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