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Exocyst Complex Component 4 (EXOC4) (N-Term) Peptide

EXOC4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976508
  • Target See all Sec8 (EXOC4) products
    Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-EXOC4 antibody (Catalog #: ARP56253_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))
    Background
    The specific function of this protein remains unknown.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: MGC27170, REC8, SEC8, SEC8L1, Sec8p

    Protein Interaction Partner: DLG3,DLGAP4,EXOC7,GRIN2B,RALA,DLG3,DLG4,EXOC3,EXOC7,GRIN2B,GTF2E2,MYC

    Protein Size: 473
    Molecular Weight
    54 kDa
    Gene ID
    60412
    NCBI Accession
    NM_001037126, NP_001032203
    UniProt
    Q8TAR2
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