Exocyst Complex Component 4 (EXOC4) (N-Term) Peptide
EXOC4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976508
Quick Overview for Exocyst Complex Component 4 (EXOC4) (N-Term) Peptide (ABIN976508)
Target
Sec8 (EXOC4)
(Exocyst Complex Component 4 (EXOC4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EXOC4 antibody (Catalog #: ARP56253_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))
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Background
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The specific function of this protein remains unknown.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: MGC27170, REC8, SEC8, SEC8L1, Sec8p
Protein Interaction Partner: DLG3,DLGAP4,EXOC7,GRIN2B,RALA,DLG3,DLG4,EXOC3,EXOC7,GRIN2B,GTF2E2,MYC
Protein Size: 473 -
Molecular Weight
- 54 kDa
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Gene ID
- 60412
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NCBI Accession
- NM_001037126, NP_001032203
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UniProt
- Q8TAR2
Target
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