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Enhancer of Zeste Homolog 2 (EZH2) Peptide

EZH2 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN976541
  • Target See all EZH2 products
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-EZH2 antibody (Catalog #: ARP38470_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    Background
    EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.

    Alias Symbols: ENX1, EZH1, KMT6, WVS2, ENX-1, KMT6A

    Protein Interaction Partner: EED,AKT1,ATP1A1,ATRX,CCDC85B,DNMT1,DNMT3A,DNMT3B,E2F6,EED,GTF3C1,HDAC1,KLHDC2,NINL,PHF1,PIN4,POLA2,PSMB6,RPN2,SMS,SUZ12,VAV1,WDR61,WSB2,ATP1A1,ATRX,CCDC85B,E2F6,EED,GTF3C1,HDAC1,HDAC2,JARID2,KLHDC2,MTF2,NINL,PHF1,PIN4,POLA2,PSMB6,RBBP4,RPN2,SNAI1,SUZ12,VAV1,WDR61,WSB2,YY1,ZMYND11

    Protein Size: 334
    Molecular Weight
    37 kDa
    Gene ID
    2146
    NCBI Accession
    NM_001203247, NP_004447
    UniProt
    Q15910
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