Enhancer of Zeste Homolog 2 (EZH2) Peptide
EZH2
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN976541
Quick Overview for Enhancer of Zeste Homolog 2 (EZH2) Peptide (ABIN976541)
Target
EZH2
(Enhancer of Zeste Homolog 2 (EZH2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EZH2 antibody (Catalog #: ARP38470_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
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Background
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EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.
Alias Symbols: ENX1, EZH1, KMT6, WVS2, ENX-1, KMT6A
Protein Interaction Partner: EED,AKT1,ATP1A1,ATRX,CCDC85B,DNMT1,DNMT3A,DNMT3B,E2F6,EED,GTF3C1,HDAC1,KLHDC2,NINL,PHF1,PIN4,POLA2,PSMB6,RPN2,SMS,SUZ12,VAV1,WDR61,WSB2,ATP1A1,ATRX,CCDC85B,E2F6,EED,GTF3C1,HDAC1,HDAC2,JARID2,KLHDC2,MTF2,NINL,PHF1,PIN4,POLA2,PSMB6,RBBP4,RPN2,SNAI1,SUZ12,VAV1,WDR61,WSB2,YY1,ZMYND11
Protein Size: 334 -
Molecular Weight
- 37 kDa
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Gene ID
- 2146
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NCBI Accession
- NM_001203247, NP_004447
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UniProt
- Q15910
Target
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