Coagulation Factor II (thrombin) (F2) (Middle Region) Peptide
F2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN976548
Quick Overview for Coagulation Factor II (thrombin) (F2) (Middle Region) Peptide (ABIN976548)
Target
Prothrombin (F2)
(Coagulation Factor II (thrombin) (F2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-F2 antibody (Catalog #: ARP41757_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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Background
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Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PT
Protein Interaction Partner: F2R,AANAT,AKR7A2,AMBP,C6,CPB2,F11,F13A1,F2,F2R,F2RL1,F2RL2,F2RL3,F5,F8,F9,FGA,GGCX,GP1BA,GP5,HGFAC,IGFBP3,IGFBP5,ITGA2B,KNG1,PLAU,PROC,PROS1,PROZ,SERPINA5,SERPINB6,SERPINB8,SERPINC1,SERPIND1,SERPINE1,SERPINE2,SERPING1,SPP1,ST13,THBD,THBS1,CPB2,F5,FGA,ITGA2B,PLAT,SERPINB6,SERPIND1,SERPINE1,SERPING1,THBD,THBS1
Protein Size: 622 -
Molecular Weight
- 65 kDa
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Gene ID
- 2147
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NCBI Accession
- NM_000506, NP_000497
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UniProt
- P00734
Target
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