F-Box and Leucine-Rich Repeat Protein 12 (FBXL12) (C-Term) Peptide
FBXL12
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FBXL12 products
- FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PTEILSSCLT MPKLRVLELQ GLGWEGQEAE KILCKGLPHC MVIVRACPKE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FBXL12 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))
- Synonyms
- Fbl12 Peptide, FBXL12 Peptide, fbl12 Peptide, 3110048D16Rik Peptide, F-box and leucine rich repeat protein 12 Peptide, F-box and leucine-rich repeat protein 12 Peptide, RNI-like superfamily protein Peptide, FBXL12 Peptide, Fbxl12 Peptide, fbxl12 Peptide, AT3G07550 Peptide
- Background
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Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Alias Symbols: FLJ20188, Fbl12
Protein Interaction Partner: FXYD3,SMAD1,TGFBR1,FXYD3
Protein Size: 326 - Molecular Weight
- 37 kDa
- Gene ID
- 54850
- NCBI Accession
- NM_017703, NP_060173
- UniProt
- Q9NXK8
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