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F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (Middle Region) Peptide

FBXL3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976717

Quick Overview for F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (Middle Region) Peptide (ABIN976717)

Target

FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-FBXL3 antibody (Catalog #: ARP43098_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

    Background

    FBXL3 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

    Alias Symbols: FBL3, FBL3A, FBXL3A

    Protein Interaction Partner: SKP1,SKP1,CDC34,CUL1,SKP1,UBE2D2

    Protein Size: 428

    Molecular Weight

    47 kDa

    Gene ID

    26224

    NCBI Accession

    NM_012158, NP_036290

    UniProt

    Q9UKT7
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