F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptide
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- Target See all FBXL3 products
- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Fbxl3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
- Synonyms
- FBL3 Peptide, FBL3A Peptide, FBXL3A Peptide, AU041772 Peptide, AW212966 Peptide, FBK Peptide, Fbl3a Peptide, Fbxl3a Peptide, Ovtm Peptide, Play68 Peptide, fbxl3 Peptide, FBXL3 Peptide, F7A7.240 Peptide, F7A7_240 Peptide, im:7153024 Peptide, zgc:103721 Peptide, F-box and leucine rich repeat protein 3 Peptide, F-box and leucine-rich repeat protein 3 Peptide, F-box and leucine-rich repeat protein 3 L homeolog Peptide, RNI-like superfamily protein Peptide, F-box and leucine-rich repeat protein 3a Peptide, FBXL3 Peptide, Fbxl3 Peptide, fbxl3.L Peptide, fbxl3 Peptide, AT5G01720 Peptide, fbxl3a Peptide
- Background
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Fbxl3 is a substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Alias Symbols: AU041772, AW212966, FBK, Fbl3a, Fbxl3a, Ovtm
Protein Size: 428 - Molecular Weight
- 49 kDa
- Gene ID
- 50789
- NCBI Accession
- NM_015822, NP_056637
- UniProt
- Q8C4V4
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