F-Box and WD Repeat Domain Containing 11 (FBXW11) Peptide
FBXW11
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976766
$160.46
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100 μg
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Quick Overview for F-Box and WD Repeat Domain Containing 11 (FBXW11) Peptide (ABIN976766)
Target
FBXW11
(F-Box and WD Repeat Domain Containing 11 (FBXW11))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FBXW11 antibody (Catalog #: ARP43129_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
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Background
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FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Alias Symbols: BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696
Protein Interaction Partner: BTRC,CDC25A,CUL1,FBXW11,GLI2,IFNAR1,NFKB1,NFKBIA,WEE1,ARIH1,ATG4B,BTRC,CDC25B,CLPX,CLSPN,CUL1,FAM123B,FBXW11,HIVEP1,HIVEP2,KHDRBS2,MYO10,NFKBIA,NRD1,NUDC,OGT,PDCD4,RPRM,SKP1,SUN2,TFAP4,TUBGCP3,USP37,USP47,WEE1,ZRANB1
Protein Size: 542 -
Molecular Weight
- 62 kDa
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Gene ID
- 23291
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NCBI Accession
- NM_012300, NP_036432
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UniProt
- Q9UKB1
Target
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