Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) Peptide
FDFT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976799
Quick Overview for Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) Peptide (ABIN976799)
Target
FDFT1
(Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FDFT1 antibody (Catalog #: ARP48630_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
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Background
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FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DGPT, ERG9, SQS, SS
Protein Interaction Partner: ANXA5,ARL6IP1,FAM101A,RUVBL2,SHPRH,TMEM43,ANXA5,ARL6IP1,Fam101a,PSTPIP1,RUVBL1,RUVBL2,SHPRH,SMNDC1,TMEM43
Protein Size: 417 -
Molecular Weight
- 48 kDa
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Gene ID
- 2222
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NCBI Accession
- NM_004462, NP_004453
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UniProt
- P37268
Target
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