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FIP1 Like 1 (FIP1L1) Peptide

FIP1L1 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN976861
  • Target See all FIP1L1 products
    FIP1L1 (FIP1 Like 1 (FIP1L1))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-FIP1L1 antibody (Catalog #: ARP41031_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FIP1L1 (FIP1 Like 1 (FIP1L1))
    Background
    FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.

    Alias Symbols: DKFZp586K0717, FLJ33619, Rhe, hFip1

    Protein Interaction Partner: RNPS1,CPSF4,CPSF4

    Protein Size: 594
    Molecular Weight
    65 kDa
    Gene ID
    81608
    NCBI Accession
    NM_030917, NP_112179
    UniProt
    Q6UN15
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