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FK506 Binding Protein 2, 13kDa (FKBP2) (N-Term) Peptide

FKBP2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976871

Quick Overview for FK506 Binding Protein 2, 13kDa (FKBP2) (N-Term) Peptide (ABIN976871)

Target

FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Origin

Human

Source

  • 1
  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-FKBP2 antibody (Catalog #: ARP58465_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

    Background

    FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.

    Alias Symbols: FKBP-13, PPIase

    Protein Interaction Partner: ARFGEF1,BAT3,C1QC,EPB41,EPB41L2,UBQLN4,ARFGEF1,ARFGEF2,BAT3,CDKN2A,EPB41L2

    Protein Size: 142

    Molecular Weight

    16 kDa

    Gene ID

    2286

    NCBI Accession

    NM_004470, NP_004461

    UniProt

    P26885
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