Fragile X Mental Retardation 1 (FMR1) (C-Term) Peptide
FMR1
Reactivity: Rat
Host: Synthetic
BP, WB
Catalog No. ABIN976953
Quick Overview for Fragile X Mental Retardation 1 (FMR1) (C-Term) Peptide (ABIN976953)
Target
FMR1
(Fragile X Mental Retardation 1 (FMR1))
Origin
Rat
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- QIGASSRPPP NRTDKEKGYV TDDGQGMGRG SRPYRNRGHG RRGPGYTSES
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Fmr1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Fragile X Mental Retardation 1 (FMR1) peptide
FMR1 Reactivity: Human, Rat, Dog, Mouse Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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Background
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Fmr1 is a translation repressor. Fmr1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression. RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.Fmr1 is associated with polysomes. Fmr1 is involved in the transport of mRNA from the nucleus to the cytoplasm. Fmr1 binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
Alias Symbols: FMRP, Fmr1
Protein Size: 593 -
Molecular Weight
- 67 kDa
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Gene ID
- 24948
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NCBI Accession
- NM_052804, NP_434691
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UniProt
- Q80WE1
Target
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