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Farnesyltransferase, CAAX Box, alpha (FNTA) Peptide

FNTA Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976962

Quick Overview for Farnesyltransferase, CAAX Box, alpha (FNTA) Peptide (ABIN976962)

Target

FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-FNTA antibody (Catalog #: ARP48521_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

    Background

    Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: FPTA, MGC99680, PGGT1A, PTAR2

    Protein Interaction Partner: ACVR1,CENPF,FNTB,GBP1,HRAS,KRAS,PTP4A3,RHOB,TGFB1,TGFBR1,ACVR1,PTP4A2,TGFB1,TGFBR1

    Protein Size: 312

    Molecular Weight

    36 kDa

    Gene ID

    2339

    NCBI Accession

    NM_001018677, NP_001018197

    UniProt

    A6NJW0
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