Farnesyltransferase, CAAX Box, alpha (FNTA) Peptide
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- Target See all FNTA products
- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FNTA antibody (Catalog #: ARP48521_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
- Background
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Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: FPTA, MGC99680, PGGT1A, PTAR2
Protein Interaction Partner: ACVR1,CENPF,FNTB,GBP1,HRAS,KRAS,PTP4A3,RHOB,TGFB1,TGFBR1,ACVR1,PTP4A2,TGFB1,TGFBR1
Protein Size: 312 - Molecular Weight
- 36 kDa
- Gene ID
- 2339
- NCBI Accession
- NM_001018677, NP_001018197
- UniProt
- A6NJW0
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