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Forkhead Box A2 (FOXA2) Peptide

FOXA2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976982

Quick Overview for Forkhead Box A2 (FOXA2) Peptide (ABIN976982)

Target

FOXA2 (Forkhead Box A2 (FOXA2))

Origin

Human

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-FOXA2 antibody (Catalog #: ARP39508_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FOXA2 (Forkhead Box A2 (FOXA2))

    Background

    FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.

    Alias Symbols: HNF3B, TCF3B

    Protein Interaction Partner: EN2,GSC,HOXA5,MIP,NCOA1,ONECUT1,OTX2,TLE1,EN2,GSC,HOXA5,LHX1,NCOA1,ONECUT1,OTX2,TLE1

    Protein Size: 457

    Molecular Weight

    50 kDa

    Gene ID

    3170

    NCBI Accession

    NM_153675, NP_710141

    UniProt

    Q9Y261
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