Forkhead Box C1 (FOXC1) Peptide
Quick Overview for Forkhead Box C1 (FOXC1) Peptide (ABIN976991)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FOXC1 antibody (Catalog #: ARP32300_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FOXC1 (Forkhead Box C1 (FOXC1))
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Background
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FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
Alias Symbols: ARA, IGDA, IHG1, FKHL7, IRID1, RIEG3, FREAC3, FREAC-3
Protein Interaction Partner: HMGB1
Protein Size: 553 -
Molecular Weight
- 57 kDa
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Gene ID
- 2296
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NCBI Accession
- NM_001453, NP_001444
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UniProt
- Q12948
Target
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