Ferritin, Light Polypeptide (FTL) Peptide
FTL
Reactivity: Human
Host: Synthetic
WB, BP
Catalog No. ABIN977126
Quick Overview for Ferritin, Light Polypeptide (FTL) Peptide (ABIN977126)
Target
FTL
(Ferritin, Light Polypeptide (FTL))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FTL antibody (Catalog #: ARP54292_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Ferritin, Light Polypeptide (FTL) peptide
FTL Reactivity: Cow Host: Escherichia coli (E. coli) WB, ELISA, IP, SDS Dithiothreitol (DTT)
Ferritin, Light Polypeptide (FTL) peptideFTL Reactivity: Horse Host: Escherichia coli (E. coli) WB, ELISA, IP, SDS Dithiothreitol (DTT)
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FTL (Ferritin, Light Polypeptide (FTL))
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Background
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FTL is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC71996, NBIA3
Protein Interaction Partner: FTH1,FTL,GADD45A,IGDCC3,KNG1,MAP3K12,MPHOSPH6,MPP6,MYOC,PTN,SMAD9,TAF10,FTH1,FTL,KNG1,MAP3K12,MPP6,PTN,SPINK7,TAF10
Protein Size: 175 -
Molecular Weight
- 20 kDa
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Gene ID
- 2512
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NCBI Accession
- NM_000146, NP_000137
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UniProt
- P02792
Target
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