Frizzled Family Receptor 7 (FZD7) Peptide
FZD7
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN977173
Quick Overview for Frizzled Family Receptor 7 (FZD7) Peptide (ABIN977173)
Target
FZD7
(Frizzled Family Receptor 7 (FZD7))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FZD7 antibody (Catalog #: ARP41251_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Frizzled Family Receptor 7 (FZD7) peptide
FZD7 Reactivity: Human, Mouse Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FZD7 (Frizzled Family Receptor 7 (FZD7))
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Background
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FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Alias Symbols: FzE3
Protein Interaction Partner: DLG1,DLG2,DLG4,MAGI3,UBQLN1,UBQLN4,DLG4,UBQLN1
Protein Size: 574 -
Molecular Weight
- 63 kDa
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Gene ID
- 8324
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NCBI Accession
- NM_003507, NP_003498
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UniProt
- O75084
Target
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