GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) Peptide
G3BP1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977181
Quick Overview for GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) Peptide (ABIN977181)
Target
G3BP1
(GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-G3BP antibody (Catalog #: ARP37713_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
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Background
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G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: G3BP, HDH-VIII
Protein Interaction Partner: CSK,G3BP1,RASA1,USP10,ASCC3,ATXN2L,C4orf43,CAPRIN1,CLNS1A,DHX40,EIF4G1,FAF1,FLNA,FLNB,G3BP1,GNL2,HAT1,HIST2H2AA3,IFRD2,KRI1,MRPL45,NOL6,NUFIP2,NUP188,NUP214,NUP62,PUF60,RASA1,RPAP2,UIMC1,USP10,UTP18,WDR36,YTHDF1
Protein Size: 466 -
Molecular Weight
- 51 kDa
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Gene ID
- 10146
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NCBI Accession
- NM_005754, NP_005745
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UniProt
- Q13283
Target
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