gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Peptide
GABRG2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977221
Quick Overview for gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Peptide (ABIN977221)
Target
GABRG2
(gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GABRG2 antibody (Catalog #: ARP35574_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
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Background
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Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. GABRG2 is the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures.Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. This gene encodes the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Alias Symbols: CAE2, ECA2, GEFSP3
Protein Interaction Partner: DRD5,GABARAP,GABRG2,PPP3CA,PRKCA,PRKCB,ZDHHC3,DRD5,GABARAP
Protein Size: 327 -
Molecular Weight
- 36 kDa
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Gene ID
- 2566
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NCBI Accession
- NM_198903, NP_944493
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UniProt
- P18507
Target
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