Gigaxonin (GAN) (Middle Region) Peptide
GAN
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GAN products
- GAN (Gigaxonin (GAN))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IYLNDQNLCI PASSSFVYGA VPIGASIYVI GDLDTGTNYD YVREFKRSTG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GAN Antibody(ARP58470_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GAN (Gigaxonin (GAN))
- Background
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This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN).
Alias Symbols: FLJ38059, GAN1, KLHL16
Protein Interaction Partner: MAP1B,TBCB,UBA1,ATG16L1,CUL3,MAP1B,RBX1,SFN,UBC
Protein Size: 597 - Molecular Weight
- 66 kDa
- Gene ID
- 8139
- NCBI Accession
- NM_022041, NP_071324
- UniProt
- Q9H2C0
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