Gigaxonin (GAN) (Middle Region) Peptide
GAN
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977266
Quick Overview for Gigaxonin (GAN) (Middle Region) Peptide (ABIN977266)
Target
GAN
(Gigaxonin (GAN))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- IYLNDQNLCI PASSSFVYGA VPIGASIYVI GDLDTGTNYD YVREFKRSTG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GAN Antibody(ARP58470_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GAN (Gigaxonin (GAN))
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Background
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This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN).
Alias Symbols: FLJ38059, GAN1, KLHL16
Protein Interaction Partner: MAP1B,TBCB,UBA1,ATG16L1,CUL3,MAP1B,RBX1,SFN,UBC
Protein Size: 597 -
Molecular Weight
- 66 kDa
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Gene ID
- 8139
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NCBI Accession
- NM_022041, NP_071324
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UniProt
- Q9H2C0
Target
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