Glycyl-tRNA Synthetase (GARS) (Middle Region) Peptide
GARS
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN977277
Quick Overview for Glycyl-tRNA Synthetase (GARS) (Middle Region) Peptide (ABIN977277)
Target
GARS
(Glycyl-tRNA Synthetase (GARS))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GARS antibody (Catalog #: ARP58758_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GARS (Glycyl-tRNA Synthetase (GARS))
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Background
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GARS catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMT2D, DSMAV, GlyRS, HMN5, SMAD1
Protein Interaction Partner: EEF1D,CD44,CELSR2,EEF1D,IARS,EEF1D,IARS
Protein Size: 739 -
Molecular Weight
- 83 kDa
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Gene ID
- 2617
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NCBI Accession
- NM_002047, NP_002038
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UniProt
- P41250
Target
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