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Glycyl-tRNA Synthetase (GARS) (Middle Region) Peptide

GARS Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN977277
  • Target See all GARS products
    GARS (Glycyl-tRNA Synthetase (GARS))
    Protein Region
    Middle Region
    Origin
    Human, Mouse
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-GARS antibody (Catalog #: ARP58758_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GARS (Glycyl-tRNA Synthetase (GARS))
    Background
    GARS catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CMT2D, DSMAV, GlyRS, HMN5, SMAD1

    Protein Interaction Partner: EEF1D,CD44,CELSR2,EEF1D,IARS,EEF1D,IARS

    Protein Size: 739
    Molecular Weight
    83 kDa
    Gene ID
    2617
    NCBI Accession
    NM_002047, NP_002038
    UniProt
    P41250
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