Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1) (N-Term) Peptide
Quick Overview for Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1) (N-Term) Peptide (ABIN977309)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- IHWDPEHSYE FKHSRPKKPR SLRIYESHVG ISSHEGKVAS YKHFTCNVLP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GBE1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GBE1 (Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1))
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Background
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The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease).
Alias Symbols: GBE
Protein Interaction Partner: PGD
Protein Size: 702 -
Molecular Weight
- 80 kDa
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Gene ID
- 2632
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NCBI Accession
- NM_000158, NP_000149
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UniProt
- Q04446
Target
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