Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) Peptide
GCLM
Reactivity: Human, Mouse
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN977334
Quick Overview for Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) Peptide (ABIN977334)
Target
GCLM
(Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GCLM antibody (Catalog #: ARP54624_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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Background
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Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GLCLR
Protein Size: 274 -
Molecular Weight
- 31 kDa
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Gene ID
- 2730
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NCBI Accession
- NM_002061, NP_002052
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UniProt
- P48507
Target
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