Growth Differentiation Factor 5 (GDF5) (C-Term) Peptide
GDF5
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977356
Quick Overview for Growth Differentiation Factor 5 (GDF5) (C-Term) Peptide (ABIN977356)
Target
GDF5
(Growth Differentiation Factor 5 (GDF5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LHVKAARARD RDYRALCDVG TAISCSRVFS SRLPADTLGL CPDAAELPGV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-VKORC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GDF5 (Growth Differentiation Factor 5 (GDF5))
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Background
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Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.
Alias Symbols: EDTP308, FLJ00289, IMAGE3455200, MGC2694, MST134, MST576, VKCFD2, VKOR
Protein Size: 92 -
Molecular Weight
- 10 kDa
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Gene ID
- 79001
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NCBI Accession
- NM_206824
Target
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