G-Elongation Factor, Mitochondrial 1 (GFM1) (Middle Region) Peptide
GFM1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all GFM1 products
- GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ISIAMRPSNK NDLEKFSKGI GRFTREDPTF KVHFDPESKE TIVSGMGELH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Gfm1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))
- Synonyms
- COXPD1 Peptide, EFG Peptide, EFG1 Peptide, EFGM Peptide, EGF1 Peptide, GFM Peptide, hEFG1 Peptide, AW545374 Peptide, D3Wsu133e Peptide, Gfm Peptide, EF-G Peptide, Efg Peptide, G elongation factor mitochondrial 1 Peptide, G elongation factor, mitochondrial 1 Peptide, GFM1 Peptide, Gfm1 Peptide
- Background
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Gfm1 is a mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Gfm1 catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Gfm1 does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
Alias Symbols: AW545374, D3Wsu133e, Gfm
Protein Size: 751 - Molecular Weight
- 83 kDa
- Gene ID
- 28030
- NCBI Accession
- NM_138591, NP_613057
- UniProt
- Q8K0D5
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