Gap Junction Protein, alpha 1, 43kDa (GJA1) Peptide
GJA1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977415
Quick Overview for Gap Junction Protein, alpha 1, 43kDa (GJA1) Peptide (ABIN977415)
Target
Connexin 43/GJA1 (GJA1)
(Gap Junction Protein, alpha 1, 43kDa (GJA1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GJA1 antibody (Catalog #: ARP36598_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
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Background
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Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.
Alias Symbols: HSS, CX43, GJAL, ODDD, AVSD3, HLHS1, DFNB38
Protein Interaction Partner: SRC,CAV1,CSK,CSNK1D,GJA3,GJA5,MAPK1,MAPK3,MAPK7,NOV,PRKCA,PRKCB,PRKCE,PRKCG,S100A1,SGSM3,SRC,TJP1,CAV1,CSNK1D,GJA1,GJA3,GJA5,MAPK7,PRKCA,PRKCE,S100A1,TJP1
Protein Size: 382 -
Molecular Weight
- 42 kDa
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Gene ID
- 2697
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NCBI Accession
- NM_000165, NP_000156
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UniProt
- Q53FJ6
Target
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