Gap Junction Protein, beta 2, 26kDa (GJB2) Peptide
GJB2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977426
Quick Overview for Gap Junction Protein, beta 2, 26kDa (GJB2) Peptide (ABIN977426)
Target
GJB2
(Gap Junction Protein, beta 2, 26kDa (GJB2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GJB2 antibody (Catalog #: ARP36608_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
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Background
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Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1, MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.
Alias Symbols: HID, KID, PPK, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A
Protein Interaction Partner: CAV1,GJB1,GJB6,CAV1
Protein Size: 226 -
Molecular Weight
- 25 kDa
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Gene ID
- 2706
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NCBI Accession
- NM_004004, NP_003995
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UniProt
- P29033
Target
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