Galactosidase, alpha (GLA) Peptide
GLA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GLA products
- GLA (Galactosidase, alpha (GLA))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GLA antibody (Catalog #: ARP54296_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GLA (Galactosidase, alpha (GLA))
- Synonyms
- GALA Peptide, Ags Peptide, zgc:101584 Peptide, MGC130872 Peptide, SMU.877 Peptide, SCF11.21 Peptide, AO090005000217 Peptide, alpha-GAL Peptide, galactosidase alpha Peptide, galactosidase, alpha Peptide, galactosidase alpha S homeolog Peptide, alpha-galactosidase Peptide, aga Peptide, alpha-galactosidase A Peptide, GLA Peptide, Gla Peptide, gla Peptide, gla.S Peptide, agaN Peptide, aga Peptide, agaL Peptide, SCO0541 Peptide, rafA Peptide, melA Peptide, galA Peptide, ANI_1_2528074 Peptide, ANI_1_1502124 Peptide, AOR_1_390174 Peptide, CpipJ_CPIJ002066 Peptide, MCYG_00962 Peptide, MCYG_00791 Peptide, Tsp_02909 Peptide, Tsp_02508 Peptide
- Background
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GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GALA
Protein Interaction Partner: GLA,OTUD4
Protein Size: 429 - Molecular Weight
- 45 kDa
- Gene ID
- 2717
- NCBI Accession
- NM_000169, NP_000160
- UniProt
- P06280
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