GM2 Ganglioside Activator (GM2A) (N-Term) Peptide
GM2A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GM2A products
- GM2A (GM2 Ganglioside Activator (GM2A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SWDNCDEGKD PAVIRSLTLE PDPIIVPGNV TLSVMGSTSV PLSSPLKVDL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GM2A Antibody(ARP46007_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GM2A (GM2 Ganglioside Activator (GM2A))
- Background
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This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Alias Symbols: SAP-3, GM2-AP
Protein Interaction Partner: GPLD1,HEXA,PLD2,HEXA
Protein Size: 193 - Molecular Weight
- 18 kDa
- Gene ID
- 2760
- NCBI Accession
- NM_000405, NP_000396
- UniProt
- P17900
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