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Glycoprotein IX (Platelet) (GP9) (Middle Region) Peptide

GP9 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN977575

Quick Overview for Glycoprotein IX (Platelet) (GP9) (Middle Region) Peptide (ABIN977575)

Target

CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    NSLQSVPPGA FDHLPQLQTL DVTQNPWHCD CSLTYLRLWL EDRTPEALLQ

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-GP9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

    Background

    This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.

    Alias Symbols: CD42a, GPIX

    Protein Interaction Partner: GP1BA,GP1BB

    Protein Size: 177

    Molecular Weight

    19 kDa

    Gene ID

    2815

    NCBI Accession

    NM_000174, NP_000165

    UniProt

    P14770
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