G Protein-Coupled Estrogen Receptor 1 (GPER) (C-Term) Peptide
GPER
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977586
Quick Overview for G Protein-Coupled Estrogen Receptor 1 (GPER) (C-Term) Peptide (ABIN977586)
Target
GPER
(G Protein-Coupled Estrogen Receptor 1 (GPER))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- SFLGETFRDK LRLYIEQKTN LPALNRFCHA ALKAVIPDST EQSDVRFSSA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GPER Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))
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Background
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This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Alias Symbols: CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPR30, LERGU, LERGU2, LyGPR, MGC99678, GPER
Protein Size: 375 -
Molecular Weight
- 42 kDa
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Gene ID
- 2852
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NCBI Accession
- NM_001098201, NP_001091671
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UniProt
- Q99527
Target
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