Glutamate Receptor 1 (GLUR1) (N-Term) Peptide
GLUR1
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN977672
Quick Overview for Glutamate Receptor 1 (GLUR1) (N-Term) Peptide (ABIN977672)
Target
Glutamate Receptor 1 (GLUR1)
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- CGALHVCFIT PSFPVDTSNQ FVLQLRPELQ EALISIIDHY KWQTFVYIYD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Gria1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Glutamate Receptor 1 (GLUR1)
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Background
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Gria1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Alias Symbols: 2900051M01Rik, AI853806, Glr-1, Glr1, GluR-A, GluRA, Glur-1, Glur1, HIPA1, GluA1, gluR-K1
Protein Size: 907 -
Molecular Weight
- 99 kDa
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Gene ID
- 14799
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NCBI Accession
- NM_001113325, NP_001106796
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UniProt
- P23818
Target
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