General Transcription Factor IIB (GTF2B) (C-Term) Peptide
GTF2B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GTF2B products
- GTF2B (General Transcription Factor IIB (GTF2B))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GTF2B antibody (Catalog #: ARP58006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GTF2B (General Transcription Factor IIB (GTF2B))
- Background
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GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TF2B, TFIIB
Protein Interaction Partner: BAX,EP300,POU3F2,THRA,UL48,VDR,BCL3,CREBBP,DHX9,EP300,ESR1,ESRRA,FOXF2,GTF2B,GTF2E1,GTF2E2,GTF2F1,GTF2F2,HSF1,IKZF1,JUN,MCM2,NCOA1,NCOA3,NCOA4,NOLC1,NR2F1,NR5A1,POLR2A,POU3F2,PSMC2,PSMC5,REL,RELA,TAF9,TBP,TBPL1,TCEA2,THRA,TRAM2,VDR,ATF4,BCL3,CREBBP,CTBP1,CTDP1,DHX9,FOXF2,GTF2E1,GTF2E2,GTF2F1,GTF2F2,GTF2H4,HSF1,HSF1,IKZF1,JUN,KLF5,MECP2,MED21,MYC,NCOA1,NCOA4,NR2F1,NR5A1,PKP2,POLR2A,POLR2H,POLR2J,POLR3A,PSMC2,REL,RELA,TAF11,TBP,TBPL1,TCEA1
Protein Size: 316 - Molecular Weight
- 35 kDa
- Gene ID
- 2959
- NCBI Accession
- NM_001514, NP_001505
- UniProt
- Q00403
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