Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3) (N-Term) Peptide
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- Target See all GUCY1B3 products
- GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IDMKVIQQRN EECDHTQFLI EEKESKEEDF YEDLDRFEEN GTQESRISPY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GCYB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))
- Background
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This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.
Alias Symbols: GUCY1B3,GUC1B3, GUCSB3, GUCY1B1,
Protein Size: 619 - Molecular Weight
- 70 kDa
- Gene ID
- 2983
- UniProt
- Q02153
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