Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3) (N-Term) Peptide
GUCY1B3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977802
Quick Overview for Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3) (N-Term) Peptide (ABIN977802)
Target
GUCY1B3
(Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- IDMKVIQQRN EECDHTQFLI EEKESKEEDF YEDLDRFEEN GTQESRISPY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GCYB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))
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Background
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This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.
Alias Symbols: GUCY1B3,GUC1B3, GUCSB3, GUCY1B1,
Protein Size: 619 -
Molecular Weight
- 70 kDa
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Gene ID
- 2983
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UniProt
- Q02153
Target
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