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H1 Histone Family, Member O, Oocyte-Specific (H1FOO) (Middle Region) Peptide

H1FOO Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN977820
  • Target See all H1FOO products
    H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    KAPKAGQGPN TKAAAPAKGS GSKVVPAHLS RKTEAPKGPR KAGLPIKASS
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-H1FOO Antibody(ARP53205_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
    Background
    H1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.

    Alias Symbols: MGC50807, osH1

    Protein Size: 346
    Molecular Weight
    36 kDa
    Gene ID
    132243
    NCBI Accession
    NM_153833, NP_722575
    UniProt
    Q8IZA3
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