H1 Histone Family, Member O, Oocyte-Specific (H1FOO) (Middle Region) Peptide
H1FOO
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all H1FOO products
- H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KAPKAGQGPN TKAAAPAKGS GSKVVPAHLS RKTEAPKGPR KAGLPIKASS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-H1FOO Antibody(ARP53205_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
- Background
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H1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Alias Symbols: MGC50807, osH1
Protein Size: 346 - Molecular Weight
- 36 kDa
- Gene ID
- 132243
- NCBI Accession
- NM_153833, NP_722575
- UniProt
- Q8IZA3
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