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Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) Peptide

HAO1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN977847
  • Target See all HAO1 products
    HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-HAO1 antibody (Catalog #: ARP42480_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
    Background
    Subcellular location of HAO1 is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.

    Alias Symbols: GOX, GOX1, HAOX1

    Protein Interaction Partner: HCVgp1

    Protein Size: 370
    Molecular Weight
    41 kDa
    Gene ID
    54363
    NCBI Accession
    NM_017545, NP_060015
    UniProt
    Q9UJM8
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