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Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) Peptide

HAO1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN977847

Quick Overview for Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1) Peptide (ABIN977847)

Target

HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-HAO1 antibody (Catalog #: ARP42480_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

    Background

    Subcellular location of HAO1 is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.

    Alias Symbols: GOX, GOX1, HAOX1

    Protein Interaction Partner: HCVgp1

    Protein Size: 370

    Molecular Weight

    41 kDa

    Gene ID

    54363

    NCBI Accession

    NM_017545, NP_060015

    UniProt

    Q9UJM8
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