Histone Deacetylase 6 (HDAC6) Peptide
HDAC6
Reactivity: Human
Host: Synthetic
BP, WB, ChIP
Catalog No. ABIN977908
Quick Overview for Histone Deacetylase 6 (HDAC6) Peptide (ABIN977908)
Target
HDAC6
(Histone Deacetylase 6 (HDAC6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HDAC6 antibody (Catalog #: ARP31451_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Background
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Alias Symbols: HD6, JM21
Protein Interaction Partner: BCL3,BCL3,BCOR,BRMS1,EP300,HDAC11,PLAA,RELB,RUNX2,SIRT2,TUBA1B,TUBA4A,TUBB,UBB,UBB,VCP,ZBTB16,BCOR,CBFA2T3,DNAJB6,DNAJB8,EEA1,EGFR,EP300,HDAC11,RELB,RUNX2,UBC,UBE2D1,UBE2D3,UBE2E1,UBE2H,ZBTB16
Protein Size: 146 -
Molecular Weight
- 16 kDa
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Gene ID
- 10013
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NCBI Accession
- NM_006044
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UniProt
- Q9UBN7
Target
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