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Homogentisate 1,2-Dioxygenase (HGD) (Middle Region) Peptide

HGD Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN977962

Quick Overview for Homogentisate 1,2-Dioxygenase (HGD) (Middle Region) Peptide (ABIN977962)

Target

HGD (Homogentisate 1,2-Dioxygenase (HGD))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

Middle Region

Characteristics

This is a synthetic peptide designed for use in combination with anti-HGD antibody (Catalog #: ARP51477_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Homogentisate 1,2-Dioxygenase (HGD) peptide
HGD Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

HGD (Homogentisate 1,2-Dioxygenase (HGD))

Background

Homogentisate 1,2-dioxygenase (HGD) gene mutations are the molecular cause of alkaptonuria, a rare hereditary disorder of the phenylalanine catabolism. The highest expression of HGD is in the prostate, small intestine, colon, and liver. The HGD gene contains 14 exons. Conflicting reports have placed the gene at 3q2, 3q13.3-q21, 3q21-q24, 3q21-q23, or 3q25-q26.Homogentisate 1,2-dioxygenase (HGD) gene mutations are the molecular cause of alkaptonuria, a rare hereditary disorder of the phenylalanine catabolism. The highest expression of HGD is in the prostate, small intestine, colon, and liver. The HGD gene contains 14 exons. Conflicting reports have placed the gene at 3q2, 3q13.3-q21, 3q21-q24, 3q21-q23, or 3q25-q26. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: AKU, HGO

Protein Interaction Partner: HGD

Protein Size: 445

Molecular Weight

50 kDa

Gene ID

3081

NCBI Accession

NM_000187, NP_000178

UniProt

Q93099

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