Hexokinase 2 (HK2) (Middle Region) Peptide
HK2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978015
Quick Overview for Hexokinase 2 (HK2) (Middle Region) Peptide (ABIN978015)
Target
Hexokinase 2 (HK2)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- QRIKENKGEE RLRSTIGVDG SVYKKHPHFA KRLHKTVRRL VPGCDVRFLR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HK2 Antibody(ARP54304_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Hexokinase 2 (HK2)
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Background
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this protein is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Alias Symbols: DKFZp686M1669, HKII, HXK2
Protein Interaction Partner: IGFBP4,PTGDS,ZBTB17,PRKCE,PTGDS,SLC2A4,UBQLN1,UBQLN4,ZBTB17,PRKCE,UBQLN1
Protein Size: 917 -
Molecular Weight
- 102 kDa
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Gene ID
- 3099
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NCBI Accession
- NM_000189, NP_000180
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UniProt
- P52789
Target
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