High Mobility Group Box 1 (HMGB1) (Middle Region) Peptide
HMGB1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978054
Quick Overview for High Mobility Group Box 1 (HMGB1) (Middle Region) Peptide (ABIN978054)
Target
HMGB1
(High Mobility Group Box 1 (HMGB1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HMGB1 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HMGB1 (High Mobility Group Box 1 (HMGB1))
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Background
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Extracellular HMGB1 is an activator of human tumor cell migration operating in concert with EGF. HMGB1 encodes a protein that is potentially involved in the regulation of lipogenic and cholesterogenic gene transcription.
Alias Symbols: DKFZp686A04236, HMG1, HMG3, SBP-1
Protein Interaction Partner: HNRNPK,MECP2,RB1,TP53,TP73,TP73,AES,AGER,AR,ATOH1,C14orf1,C1orf103,CASP3,CEBPB,CRMP1,CSNK1A1,CTCF,CUX1,DNMT1,ERF,FOXA3,FOXC1,HES1,HNRNPK,HOXD9,HR,IRF2,MECP2,MNT,NCAN,NEUROD6,NFKB1,PLAT,PLG,POU5F1,PPP2R3A,PRKCA,PRKDC,RAG1,RASSF4,RB1,RBPJ,RELA,RFX1,SIX5,SOX
Protein Size: 215 -
Molecular Weight
- 25 kDa
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Gene ID
- 3146
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NCBI Accession
- NM_002128, NP_002119
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UniProt
- P09429
Target
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