Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) Peptide
HNRNPC
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN978090
Quick Overview for Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) Peptide (ABIN978090)
Target
HNRNPC
(Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- KMESEAGADD SAEEGDLLDD DDNEDRGDDQ LELKDDEKEP EEGEDDRDSA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Hnrnpc Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
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Background
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Hnrnpc binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. Hnrnpc may play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Hnrnpc interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
Alias Symbols: AL022939, D14Wsu171e, Hnrpc, Hnrpc1, Hnrpc2, hnRNPC1, hnRNPC2, hnrnp-C
Protein Size: 313 -
Molecular Weight
- 34 kDa
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Gene ID
- 15381
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NCBI Accession
- NM_016884, NP_058580
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UniProt
- Q9Z204
Target
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