Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (C-Term) Peptide
HNRNPU
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978094
$160.46
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100 μg
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Quick Overview for Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (C-Term) Peptide (ABIN978094)
Target
HNRNPU
(Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- EITYVELQKE EAQKLLEQYK EESKKALPPE KKQNTGSKKS NKNKSGKNQF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HNRNPU Antibody(ARP40518_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
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Background
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HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism.
Alias Symbols: HNRPU, SAF-A, U21.1, hnRNP U
Protein Interaction Partner: ACTB,CR2,ACTB,BTRC,CASP3,CD5,CR2,ELL,EP300,GRIN1,GRIN2D,GTF2H1,NDN,NDRG1,NR3C1,POU3F4,PRMT1,PTPN11,SMN2,SREK1,STAU1,SYK,YAP1,ZNF689,CDK7,CDK9,EP300,GPN1,GTF2F1,HNRNPH1,MAX,MYC,NDN,NR3C1,POLR2A,POLR2J,POU3F4,PRMT1,RUVBL2,SFN
Protein Size: 825 -
Molecular Weight
- 90 kDa
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Gene ID
- 3192
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NCBI Accession
- NM_031844, NP_114032
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UniProt
- Q00839
Target
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