Histamine Receptor H1 (HRH1) (Middle Region) Peptide
HRH1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978241
Quick Overview for Histamine Receptor H1 (HRH1) (Middle Region) Peptide (ABIN978241)
Target
HRH1
(Histamine Receptor H1 (HRH1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- ENPKGDAKKP GKESPWEVLK RKPKDAGGGS VLKSPSQTPK EMKSPVVFSQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HRH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HRH1 (Histamine Receptor H1 (HRH1))
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Background
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Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: H1-R, hisH1
Protein Size: 487 -
Molecular Weight
- 56 kDa
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Gene ID
- 3269
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NCBI Accession
- NM_000861, NP_000852
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UniProt
- P35367
Target
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